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Hichem Sebai Selected Research

Loperamide (Imodium)

9/2022Extraction of Pectin from Orange Peel and Study of Its Protective Effect Against Loperamide-Induced Impaired Gastrointestinal Motor Functions and Oxidative Stress in Rats.
1/2020Purgative/laxative actions of Globularia alypum aqueous extract on gastrointestinal-physiological function and against loperamide-induced constipation coupled to oxidative stress and inflammation in rats.
7/2019Modulating and opposite actions of two aqueous extracts prepared from Cinnamomum cassia L. bark and Quercus ilex L. on the gastrointestinal tract in rats.
10/2018Ficus carica aqueous extract alleviates delayed gastric emptying and recovers ulcerative colitis-enhanced acute functional gastrointestinal disorders in rats.
6/2018Opposite Effect of Opuntia ficus-indica L. Juice Depending on Fruit Maturity Stage on Gastrointestinal Physiological Parameters in Rat.
1/2018Reverse Effect of Opuntia ficus-indica L. Juice and Seeds Aqueous Extract on Gastric Emptying and Small-Bowel Motility in Rat.
5/2017Role of laxative and antioxidant properties of Malva sylvestris leaves in constipation treatment.
1/2017Vinblastine, an anticancer drug, causes constipation and oxidative stress as well as others disruptions in intestinal tract in rat.

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Hichem Sebai Research Topics

Disease

14Body Weight (Weight, Body)
09/2022 - 12/2009
11Diarrhea
04/2022 - 03/2014
10Constipation
09/2022 - 01/2017
8Inflammation (Inflammations)
07/2022 - 09/2016
6Ulcer
05/2022 - 03/2017
5Gastrointestinal Diseases (Functional Gastrointestinal Disorders)
03/2022 - 01/2017
5Endotoxemia
04/2011 - 11/2008
4Peptic Ulcer (Peptic Ulcers)
05/2022 - 05/2017
3Stomach Ulcer (Gastric Ulcer)
05/2022 - 08/2017
3Colitis
07/2021 - 10/2018
3Septic Shock (Toxic Shock Syndrome)
04/2011 - 04/2009
2Fibrosis (Cirrhosis)
07/2022 - 04/2017
2Wounds and Injuries (Trauma)
05/2022 - 09/2020
2Ulcerative Colitis
07/2021 - 10/2018
2Digestive System Diseases
03/2018 - 03/2014
2Esophagitis
03/2018 - 09/2016
2Hemorrhoids
05/2017 - 12/2016
2Obesity
03/2017 - 03/2011
1Pulmonary Fibrosis (Fibrosing Alveolitis)
07/2022
1Encephalitis (Encephalitis, Rasmussen)
07/2022
1Edema (Dropsy)
07/2021
1Hemorrhage
07/2021
1Helminthiasis (Helminthiases)
04/2021
1Inflammatory Bowel Diseases (Inflammatory Bowel Disease)
01/2021
1Glioblastoma (Glioblastoma Multiforme)
01/2021
1Gastritis
10/2020
1Gastroenteritis
07/2019
1Mucositis
05/2018
1Hemolysis
04/2018

Drug/Important Bio-Agent (IBA)

21AntioxidantsIBA
07/2022 - 03/2014
9EnzymesIBA
07/2022 - 03/2014
8Loperamide (Imodium)FDA LinkGeneric
09/2022 - 01/2017
8CatalaseIBA
07/2022 - 03/2014
8Superoxide DismutaseIBA
07/2022 - 03/2014
8Reactive Oxygen Species (Oxygen Radicals)IBA
07/2022 - 11/2008
8Ethanol (Ethyl Alcohol)IBA
05/2022 - 03/2017
7Castor Oil (Oil, Castor)IBA
10/2021 - 03/2014
5ResveratrolIBA
04/2011 - 11/2008
5LipopolysaccharidesIBA
04/2011 - 04/2009
4LaxativesIBA
09/2022 - 05/2017
4Glutathione PeroxidaseIBA
05/2022 - 03/2014
4Proteins (Proteins, Gene)FDA Link
07/2021 - 11/2008
4Charcoal (Charbon)IBA
10/2018 - 09/2015
4Glucose (Dextrose)FDA LinkGeneric
10/2017 - 03/2017
3Hydrogen Peroxide (Hydroperoxide)FDA LinkGeneric
05/2022 - 03/2017
3Sulfhydryl Compounds (Thiols)IBA
05/2022 - 08/2017
3Malondialdehyde (Propanedial)IBA
05/2022 - 03/2014
3Dextran SulfateIBA
01/2021 - 10/2018
3Membrane LipidsIBA
04/2011 - 11/2008
3GlycolipidsIBA
04/2011 - 04/2009
3DNA (Deoxyribonucleic Acid)IBA
04/2011 - 11/2008
2CytokinesIBA
07/2022 - 07/2021
2Bleomycin (Blenoxane)FDA LinkGeneric
07/2022 - 04/2017
2AstringentsIBA
03/2022 - 12/2016
2Glutathione (Reduced Glutathione)IBA
10/2021 - 07/2021
2Interleukin-6 (Interleukin 6)IBA
07/2021 - 04/2018
2Methanol (Carbinol)IBA
01/2021 - 09/2015
2PhytochemicalsIBA
09/2020 - 07/2019
2Corn Oil (Oil, Corn)IBA
06/2020 - 01/2018
2Cathartics (Purgatives)IBA
01/2020 - 01/2018
2Vinblastine (Vinblastine Sulfate)FDA Link
07/2019 - 01/2017
2Pharmaceutical PreparationsIBA
12/2017 - 01/2017
2IronIBA
03/2017 - 04/2011
2AntidiarrhealsIBA
09/2015 - 03/2014
2AlloxanIBA
02/2015 - 12/2013
2Nitric Oxide (Nitrogen Monoxide)FDA Link
07/2010 - 11/2008
1PectinsIBA
09/2022
1estragole (methyl chavicol)IBA
09/2022
1Transaminases (Aminotransferases)IBA
05/2022
1C-Reactive ProteinIBA
05/2022
1Omeprazole (Prilosec)FDA LinkGeneric
05/2022
1Alkaline PhosphataseIBA
05/2022
1Famotidine (Pepcid)FDA LinkGeneric
03/2022
1Peroxidase (Myeloperoxidase)IBA
07/2021
1Glutathione Transferase (Glutathione S-Transferase)IBA
07/2021
1Acetic Acid (Vinegar)FDA LinkGeneric
07/2021
1Albendazole (Albenza)FDA Link
04/2021
1Sulfasalazine (Azulfidine)FDA LinkGeneric
09/2020
1Cys(2)-CysNH2(5)- enkephalinIBA
07/2019
1Indomethacin (Indometacin)FDA LinkGeneric
07/2019
1Phenolsulfonphthalein (Phenol Red)IBA
06/2018
1Capecitabine (Xeloda)FDA Link
05/2018
1Fluorouracil (Carac)FDA LinkGeneric
05/2018
1ProdrugsIBA
05/2018
1Superoxides (Superoxide)IBA
04/2018
1Interleukin-8 (Interleukin 8)IBA
04/2018
1Malathion (Karbofos)FDA LinkGeneric
01/2018
1Irinotecan (Camptosar)FDA LinkGeneric
12/2017
1Gum Arabic (Acacia, Gum)FDA Link
10/2017
1ElectrolytesIBA
10/2017
1Cyclooxygenase 2 (Cyclooxygenase-2)IBA
08/2017
1Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
08/2017
1HesperidinIBA
08/2017
1Glyburide (Glibenclamide)FDA LinkGeneric
06/2017
1Fatty Acids (Saturated Fatty Acids)IBA
05/2017

Therapy/Procedure

5Oral Administration
05/2022 - 09/2015
3Traditional Medicine (Folk Remedies)
10/2020 - 03/2014
1Complementary Therapies (Alternative Medicine)
03/2018
1Drug Therapy (Chemotherapy)
12/2017
1Aftercare (After-Treatment)
06/2017